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Literature summary extracted from

  • Seo, M.; Song, M.; Seok, Y.M.; Kang, S.H.; Lee, H.A.; Sohn, U.D.; Kim, I.K.
    Lysine acetyltransferases cyclic adenosine monophosphate response element-binding binding protein and acetyltransferase p300 attenuate transcriptional activity of the mineralocorticoid receptor through its acetylation (2015), Clin. Exp. Pharmacol. Physiol., 42, 559-566.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.1.32 pharmacology cyclic adenosine monophosphate response element-binding binding protein and p300 are lysine acetyltransferases responsible for the regulation of mineralocorticoid receptor providing therapeutic targets for the treatment of hypertension Homo sapiens

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.3.1.32 nuclear enzyme overexpression in HEK-293 cells Homo sapiens

Protein Variants

EC Number Protein Variants Comment Organism
2.3.1.32 additional information in human embryonic kidney 293 cells, overexpression of cyclic adenosine monophosphate response element-binding binding protein, CBP, or p300, but not p300/CBP-associated factor, increases mineralocorticoid receptor acetylation and decreases expression of mineralocorticoid receptor target genes Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.32 nucleus
-
 Homo sapiens 5634
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.32 Homo sapiens
-
-
-

Synonyms

EC Number Synonyms Comment Organism
2.3.1.32 acetyltransferase p300
-
 Homo sapiens
2.3.1.32 Cbp
-
 Homo sapiens
2.3.1.32 cyclic adenosine monophosphate response element-binding binding protein
-
 Homo sapiens
2.3.1.32 lysine acetyltransferase
-
 Homo sapiens
2.3.1.32 p300
-
 Homo sapiens

General Information

EC Number General Information Comment Organism
2.3.1.32 physiological function the acetyltransferases cyclic adenosine monophosphate response element-binding binding protein (CBP) and acetyltransferase p300 attenuate transcriptional activity of the mineralocorticoid receptor through its acetylation Homo sapiens